The HIV/AIDS Nightline responds to calls annually from all over the United States. People call for many reasons: people just testing HIV positive, people in feeling isolated and/or concerned about their medications, caregivers buckling under the stress of caring for a loved one at home, and people concerned about the HIV risks. What makes the Nightline unique is the hours. For people receiving their HIV test results after work at a clinic, to people just having a night of unsafe sexual exposure, the program is often the only resource open for immediate care.